The best Side of ceesdekker

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Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules

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Nanofabrication of electrodes with sub-five nm spacing for transport experiments on solitary molecules and metallic clusters

2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and initial at any time research of your dynamics DNA supercoils and the invention of supercoil hopping

Our research ranges from the biophysics of DNA to synthetic cells and further than. Be sure to take a look underneath for the spectrum of our latest initiatives.

We use nanofabricated microfluidic buildings to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the elemental role of spatial confinement on the molecular and cellular degree. Our assignments include things like the subsequent:

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There was 1 problem while — we did not notice any measurable electrical conduction from The only polymer molecules. We concluded that at the single-molecule amount, conducting polymers have been really not these types of wonderful conductors, which was fairly disappointing. We thus broadened our look at to try to search out a lot more promising molecules.

[14] In 2005 Dekker became linked to Netherlands-large conversations about Smart Design and ceesdekker style, a movement that he has because clearly distanced himself from. Dekker advocates that science and faith are certainly not in opposition but might be harmonized.

‘That issues the artificial mobile, as A part of the Dutch BaSyC initiative. Craig Venter looked top-down in Those people times and identified about 5 hundred genes that happen to be minimally essential for any functioning mobile. We want to glimpse base-up: how do we shift from a few molecules to an entire biological procedure?

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Solid-condition nanopores have tested to get a remarkably functional probe for single-molecule Investigation of DNA. I will describe several of our current results – specifically DNA knots – and also our endeavours to increase the abilities of solid-state nanopores even even further, in the route of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.

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